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KMID : 0378019740170081115
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New Medical Journal
1974 Volume.17 No. 8 p.1115 ~ p.1120
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THE EFFECTS OF COMPOUND OF ACONITE AND SULFUR ON HANGOVER SYNDROME
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曺皓哲/Cho, Ho-Chul
朴宗漢/李時炯/Park, Jong-han/lee, Si-Hyung
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Abstract
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Aconite has long been used in the herb-medicine, though its biogenic mechanism is still remained obscure.
"Gollin" is composed with the extract of aconiti tuber, chemically processed sulfur, mica and silicate. We evaluated the clinical effectiveness of Gollin on the hangover after heavy drinking.
Sixty of normal, healthy, male volunteers, who were considered as a "Social drinker", aged between 22 to 48, were selected for this experiment. After the light evening meal on the weekend, they were instructed to fill out "Hangover Scale", then group was divided into two: Gollin and Placebo, and given the various kind of alcohol beverage in sufficient amount to get drunk. In the following morning, they were again told to fill out the same Hangover Scale about thier present condition on hangover.
In comparing the results in two groups:
1) Gollin was found to be highly effective in reducing hangover syndrome, esp. of CNS and GIT.
2) Gollin aggrevated the certain symptomes like diarrhea and feeling of floating sense, however.
3) The effectoveness of Gollin on hangover might be explained either with its enhancing capacity of blood ethanol clearence or tranquilizing effect on CNS, or both.
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